Kyoto classification of gastritis: Advances and future perspectives in endoscopic diagnosis of gastritis

Table 2 Diagnostic performance of Kyoto classification for Helicobacter pylori infection

	Ref.	Country	No. of patients	Sensitivity	Specificity	Accuracy
Non-infection
RAC	Garcés-Durán et al[22], 2019	Spain	140	100	49.0	65.0
	Yoshii et al[17], 2020	Japan	485	89.1	79.8	85.6
	Zhao et al[19], 2020	China	583	62.4	73.7	69.3
	Ebigbo et al[23], 2021	Germany	200	80.8	57.4	-
	Fiuza et al[20], 2021	Brazil	187	70.7	87.2	74.9
	Glover et al[24], 2021	UK	153	78.4	64.3	75.8
	Yuan et al[21], 2021	China	165	51.4	96.7	76.4
	Hirai et al[18], 2021	Japan	1761	93.2	83.2	90.6
Current infection
Atrophy	Toyoshima et al[27], 2018	Japan	136	82.6	85.8	85.3
	Zhao et al[19], 2020	China	583	54.9	61.1	58.5
	Ebigbo et al[23], 2021	Germany	200	80.4	69.7	-
Intestinal metaplasia	Toyoshima et al[27], 2018	Japan	136	39.1	95.6	86.0
Enlarged folds	Toyoshima et al[27], 2018	Japan	136	17.4	99.1	85.3
	Yoshii et al[17], 2020	Japan	494	23.1	96.6	85.0
Nodularity	Toyoshima et al[27], 2018	Japan	136	8.7	100	84.6
	Yoshii et al[17], 2020	Japan	494	6.4	98.3	83.8
	Toyoshima et al[28], 2020	Japan	265	33.3	99.6	89.1
	Fiuza et al[20], 2021	Brazil	187	10.6	98.6	76.5
Diffuse redness	Toyoshima et al[27], 2018	Japan	136	52.2	93.8	86.8
	Yoshii et al[17], 2020	Japan	485	60.0	94.7	89.7
	Zhao et al[19], 2020	China	583	20.3	97.6	65.0
	Fiuza et al[20], 2021	Brazil	187	80.9	73.6	75.4
Total Kyoto score	Toyoshima et al[27], 20181	Japan	136	78.3	92.0	89.7
	Sumi et al[30], 20222	Japan	561	98.7	98.4	98.6

¹The total Kyoto score ≥ 2 is defined as current infection.

²The total Kyoto score ≥ 1 is defined as current infection.

RAC: Regular arrangement of collecting venules.