Transjugular intrahepatic portosystemic shunt vs conservative treatment for recurrent ascites: A propensity score matched comparison

Table 4 Sensitivity analysis: Multivariate regressions (main effects only)

Variable	Estimate	SE	P value	Estimate	SE	P value
	Complete model			Best model
Mortality
Intercept	3.63	3.27	0.268	4.39	3.22	0.173
Creatinine	1.59 × 10-3	1.37 × 10-3	0.246	1.99 × 10-3	1.32 × 10-3	0.132
Bilirubin	7.26 × 10-4	1.10 × 10-3	0.505	-	-	-
INR	3.49 × 10-1	2.15 × 10-1	0.104	3.47 × 10-1	2.12 × 10-1	0.101
CRP	3.27 × 10-3	3.10 × 10-3	0.292	-	-	-
Leucocytes	7.01 × 10-2	2.64 × 10-2	0.008	7.84 × 10-2	2.53 × 10-2	0.002
HE 1-2	-2.88 × 10-1	4.28 × 10-1	0.500	-2.67 × 10-1	4.1 × 10-1	0.523
HE 3-4	2.24	3.56 × 10-1	< 0.001	2.26	3.50 × 10-1	< 0.001
Albumin	-9.61 × 10-2	2.76 × 10-2	< 0.001	-1.02 × 10-1	2.72 × 10-2	< 0.001
Sodium	-6.21 × 10-2	2.45 × 10-2	0.011	-6.51 × 10-2	2.45 × 10-2	0.004
Age	1.22 × 10-4	4.24 × 10-5	0.004	1.16 × 10-4	4.04 × 10-5	0.004
TIPS	-7.29 × 10-1	4.12 × 10-1	0.077	-8.22 × 10-1	4.01 × 10-1	0.040
ACLF
Intercept	-1.822	2.713	0.502	-2.70	8.51 × 10-1	0.002
Creatinine	-1.06 × 10-3	1.21 × 10-3	0.384	-	-	-
Bilirubin	2.81 × 10-3	9.50 × 10-4	0.003	2.99 × 10-3	8.69 × 10-4	0.001
INR	2.16 × 10-1	2.01 × 10-1	0.281	-	-	-
CRP	5.21 × 10-3	2.58 × 10-3	0.043	4.67 × 10-3	2.39 × 10-3	0.050
Leucocytes	6.28 × 10-3	2.43 × 10-2	0.780	-	-	-
HE 1-2	1.22 × 10-1	3.06 × 10-1	0.690	1.47 × 10-1	3.02 × 10-1	0.627
HE 3-4	1.62	3.01 × 10-1	< 0.001	1.63	2.94 × 10-1	< 0.001
Albumin	-3.80 × 10-2	2.00 × 10-2	0.058	-3.98 × 10-2	1.99 × 10-2	0.046
Sodium	-1.03 × 10-2	1.98 × 10-2	0.603	-	-	-
Age	6.39 × 10-5	3.11 × 10-5	0.039	5.63 × 10-5	2.96 × 10-5	0.057
TIPS	5.17 × 10-1	2.64 × 10-1	0.050	4.39 × 10-1	2.55 × 10-1	0.085

Dependent variables were in-hospital mortality (upper panel) and any increase in acute on chronic liver failure grade (lower panel). The full models (left side) included all parameters used for propensity score matching as covariates. After stepwise backward elimination by Akaike information criterion, a model (best model, right side) was selected for each dependent variable. ACLF: Acute on chronic liver failure; TIPS: Transjugular intrahepatic portosystemic shunt.