Transjugular intrahepatic portosystemic shunt vs conservative treatment for recurrent ascites: A propensity score matched comparison

Table 3 Changes of acute on chronic liver failure grade during hospital stay and in-hospital mortality (matched groups)

Event	No TIPS	TIPS	P value/OR (95%CI)
Hospital stay (d)	10 (1-78)	14 (3-64)	P < 0.001
Highest ACLF grade			P = 0.041
-No ACLF	157 (73%)	144 (67%)
-ACLF 1	47 (22%)	50 (23%)
-ACLF 2	8 (4%)	15 (7%)
-ACLF 3	2 (1%)	5 (2%)
-Any ACLF	57 (27%)	70 (33%)
Mortality by ACLF
-Over all	13/214 (6.1%)	11/214 (5.1%)	OR: 0.84 (0.33 -2.08)
-No ACLF	3/157 (1.9%)	0/144 (0%)	OR: 0 (0.00 -2.63)
-ACLF 1	3/47 (6.4%)	4/50 (8%)	OR: 1.27 (0.20 -9.18)
-ACLF 2	6/8 (75%)	3/15 (20%)	OR: 0.09 (0.01 -0.87)
-ACLF 3	1/2 (50%)	4/5 (80%)	OR: 3.16 (0.03 -389.17)
-Any ACLF	10/57 (17.5%)	11/70 (15.7%)	OR: 0.88 (0.31-2.52)
Increase in ACLF grade			P = 0.03
-No increase	191 (89.3%)	176 (82.2%)
-1 grade	18 (8.4%)	28 (13.1%)
-2 grades	4 (1.9%)	7 (3.3%)
-3 grades	1 (0.5%)	3 (1.4%)
Mortality by ACLF increase
-No increase	5/191 (2.6%)	2/176 (1.1%)	OR: 0.43 (0.04-2.66)
-1 grade	4/18 (22.2%)	5/28 (17.9%)	OR: 0.77 (0.14-4.55)
-2 grades	3/4 (75.0%)	2/7 (20.0%)	OR: 0.16 (0.003-3.50)
-3 grades	1/1 (100%)	2/3 (66.7%)	OR: 0 (0.00-116.8)
-Any increase	8/23 (34.8%)	9/38 (23.7%)	OR: 0.58 (0.16-2.14)

OR: Odds ratio; ACLF: Acute on chronic liver failure; TIPS: Transjugular intrahepatic portosystemic shunt.