Pancreatic acinar cell carcinoma: A comprehensive review

Figure 2 American Joint Committee on Cancer 8^th Edition cancer staging for exocrine pancreatic tumor such as pancreatic acinar cell carcinoma. A: Stage 0 (TNM: Tis, N0, M0). Tis = Carcinoma in situ. N0 = No regional lymph node metastases. M0 = No distant metastasis; B: Stage IA (TNM: T1, N0, M0). T1 = Tumor ≤ 2 cm in greatest dimension. N0 = No regional lymph node metastases. M0 = No distant metastasis; C: Stage IB (TNM: T2, N0, M0). T2 = Tumor > 2 cm and ≤ 4 cm in greatest dimension. N0 = No regional lymph node metastases. M0 = No distant metastasis; D: Stage IIA (TNM: T3, N0, M0). T3 = Tumor > 4 cm in greatest dimension. N0 = No regional lymph node metastases. M0 = No distant metastasis; E: Stage IIB (TNM: T 1/2/3, N1, M0). T 1/2/3 = Tumor ≤ 2 cm > 4 cm in greatest dimension. N1 = Metastasis in one to three regional lymph nodes. M0 = No distant metastasis; F: Stage III (TNM: T 1/2/3, N2, M0 or T4, Any N, M0). T 1/2/3 = Tumor ≤ 2 cm > 4 cm in greatest dimension. N2 = Metastasis in four or more regional lymph nodes. T4 = Tumor involves celiac axis, superior mesenteric artery, and common hepatic artery, regardless of size; G: Stage IV (TNM: Any T, Any N, M1). M1 = Distant metastasis. T = Primary tumor; N = Regional lymph node; M = Distant metastasis.