Histopathological assessment of the microscopic activity in inflammatory bowel diseases: What are we looking for?

Table 6 Inflammatory Bowel Disease-Distribution, Chronicity, Activity score

Histopathological variable	Grade
Distribution	0 = Normal; 1 = < 50% of tissue affected per same biopsy site; 2 = > 50% of tissue affected per same biopsy
Chronicity	0 = Normal; 1 = Crypt distortion and/or mild lymphoplasmacytosis; 2 = Marked lymphoplasmacytosis and/or basal plasmacytosis
Activity	0 = Normal; 1 = Two or more neutrophils in lamina propria in one high-power field and/or any presence of intraepithelial neutrophils; 2 = Crypt abscesses, erosions, ulcers

Each variable is scored independently.