Dynamic blood presepsin levels are associated with severity and outcome of acute pancreatitis: A prospective cohort study

Table 3 Time-specific area under the receiver operating characteristic curve of presepsin for prediction of moderately severe and severe acute pancreatitis

Time point	Cutoff (pg/mL)	Sensitivity	Specificity	PPV	NPV	AUROC (95%CI)	P value
Day 3	657.5	92.9%	71.4%	76.5%	90.9%	0.827 (0.730-0.923)	< 0.001
Day 5	593.5	84.6%	80.4%	81.2%	83.9%	0.848 (0.751-0.945)	< 0.001
Day 7	601.5	72.7%	89.8%	87.7%	76.7%	0.867 (0.756-0.977)	< 0.001

AUROC: Area under the receiver operating characteristic curve; NPV: Negative predictive value; PPV: Positive predictive value.