Gut microbiota of hepatitis B virus-infected patients in the immune-tolerant and immune-active phases and their implications in metabolite changes

doi:10.3748/wjg.v28.i35.5188

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Sep 21, 2022; 28(35): 5188-5202
Published online Sep 21, 2022. doi: 10.3748/wjg.v28.i35.5188

Table 2 Species richness indices in the fecal samples

Group	Healthy controls, n = 14	IT phase HBV infection, n = 13	IA phase HBV infection, n = 10	P value
OTUs	633	662	489
α-diversity indexes, median
Chao1	264.310	233.825	227.000	0.924
Shannon	5.020	4.720	4.705	1.739
Simpson	0.940	0.885	0.915	1.666

IT: Immune-tolerant; IA: Immune-active; HBV: Hepatitis B virus; OTUs: Operational taxonomic units.

Citation: Li YN, Kang NL, Jiang JJ, Zhu YY, Liu YR, Zeng DW, Wang F. Gut microbiota of hepatitis B virus-infected patients in the immune-tolerant and immune-active phases and their implications in metabolite changes. World J Gastroenterol 2022; 28(35): 5188-5202
URL: https://www.wjgnet.com/1007-9327/full/v28/i35/5188.htm
DOI: https://dx.doi.org/10.3748/wjg.v28.i35.5188