Pregnancy and fetal outcomes of chronic hepatitis C mothers with viremia in China

Table 5 Risk factors associated with fetal negative outcomes

Clinical variables	Case/exposed1	Crude OR (95%CI)	Adjusted OR (95%CI)
Head circumference ≤ 33 cm at birth
Maternal age, n (%)
< 35	118 /194 (60.8)	1	1
≥ 35	18 /194 (9.3)	1.1 (0.4-2.8); P = 0.82	2.0 (0.7-5.7); P = 0.19
Nulliparity, n (%)
No	53/194 (27.3)	1	1
Yes	83 /194 (42.8)	1.9 (1.0-3.6); P = 0.04	2.4 (1.2-4.9); P = 0.01
BMI, n (%)
< 30	120/194 (61.9)	1	1
≥ 30	16/194 (8.2)	0.4 (0.2-0.8); P = 0.008	0.3 (0.1-0.7); P = 0.003
HCV infection, n (%)
No	75/194 (38.7)	1	1
Yes	61/194 (31.4)	1.8 (0.9-3.5); P = 0.08	2.1 (1.1-4.3); P = 0.03
Intertuberous diameter, n (%)
≥ 8.5	85/194 (43.8)	1	1
< 8.5	51/194 (26.3)	1.1 (0.6-2.0); P = 0.86	1.0 (0.5-2.0); P = 0.75
Weight at birth ≤ 3250 gms
Age, n (%)
< 35	88/194 (45.4)	1	1
≥ 35	13/194 (6.7)	1.0 (0.4-2.3); P > 0.99	1.7 (0.6-4.3); P = 0.29
Nulliparity, n (%)
No	39/194 (20.1)	1	1
Yes	62/194 (32.0)	1.6 (0.9-2.8); P = 0.13	1.8 (0.9-3.4); P = 0.07
BMI, n (%)
< 30	88/194 (45.4)	1	1
≥ 30	13 /194 (6.7)	0.6 (0.3-1.2); P = 0.16	0.5 (0.2-1.1); P = 0.09
HCV infection HCV, n (%)
No	52/194 (26.8)	1	1
Yes	49/194 (25.3)	2.0 (1.1-3.5); P = 0.02	2.2 (1.2-4.0); P = 0.01
Intertuberous diameter, n (%)
≥ 8.5	61/194 (31.4)	1	1
< 8.5	40/194 (20.6)	1.2 (0.7-2.2); P = 0.46	1.1 (0.6-2.1); P = 0.66

¹Case/exposed: The case refers to the number of patients who presented with the specified variable and the Exposed refers to the total number of patients in the entire study cohort.

BMI: Body mass index; OR: Odds ratio.