Pregnancy and fetal outcomes of chronic hepatitis C mothers with viremia in China

Table 1 The demographic and clinical characteristics of mothers and infants

Variables presented with n (%), mean ± SD, or specified	HCV mothers with viremia (n = 79)1	Healthy mothers (n = 115)1	P value
Maternal characteristics
Age (yr)	25.8 ± 4.7	29.4 ± 4.9	< 0.001
< 20	2/79 (2.5)	0/115 (0.0)	0.003
20-34	73/79 (92.4)	94/115 (81.7)
≥ 35	4/79 (5.1)	21/115 (18.3)
Height, cm	159.6 ± 3.8	160.9 ± 4.0	0.02
Pre-pregnancy BMI	27.4 ± 3.4	27.5 ± 3.1	0.80
< 23	4/79 (5.1)	3/115 (2.6)	0.44
23-29	53/79 (67.1)	86/115 (74.8)
≥ 29	22/79 (27.8)	26/115 (22.6)
History of miscarriage	1/79 (1.3)	1/115 (0.9)	> 0.99
History of stillbirth	2/79 (2.5)	2/115 (1.7)	> 0.99
Previous uterine surgery	28/79 (35.4)	35/115 (30.4)	0.46
Parity
0-1	47/79 (59.5)	62/115 (53.9)	0.44
≥ 2	32/79 (40.5)	53/115 (46.1)
Plurality
0-1	47/79 (59.5)	62/115 (53.9)	0.44
> 2	32/79 (40.5)	53/115 (46.1)
Gestational (days)	273.8 ± 9.5	276.0 ± 9.1	0.11
Interspinous distance, median (IRQ), cm	25.0 (24.0, 25.0)	25.0 (24.0, 25.0)	0.23
Intercristal distance, median (IRQ), cm	27.0 (27.0, 28.0)	27.0 (27.0, 28.0)	0.40
External conjugate, median (IRQ), cm	20.0 (20.0, 21.0)	20.0 (20.0, 21.0)	0.33
Intertuberous diameter, median (IRQ), cm	8.5 (8.0, 8.5)	8.5 (8.0, 8.5)	0.006
< 8.5	38/79 (48.1)	34/115 (29.6)	0.009
≥ 8.5	41/79 (51.9)	81/115 (70.4)
Hemoglobin, median (IRQ), g/L	111.0 (100.0, 119.0)	110.0 (100.0, 119.0)	0.88
< 110	37/79 (46.8)	51/115 (44.3)	0.73
≥ 110	42/79 (53.2)	64/115 (55.7)
Platelet, median (IRQ), × 109/L	207.0 (166.0, 242.0)	201.0 (167.0, 242.0)	0.95
Prothrombin time, median (IRQ), seconds	10.6 (10.1, 11.1)	10.5 (10.0, 11.1)	0.40
ALT at delivery, U/L	26.3 ± 20.1	16.6 ± 56.7	0.15
HCV RNA at delivery, IU/mL	19, 217, 509 ± 35, 745, 723	-	-

¹All mothers in the study had a singleton pregnancy.

HCV: Hepatitis C virus; ALT: Alanine aminotransferase; IRQ: Interquartile range; BMI: Body mass index.