Diagnosis, treatment, and current concepts in the endoscopic management of gastroenteropancreatic neuroendocrine neoplasms

Table 3 Characteristics of the subtypes of neuroendocrine neoplasms of the stomach

Characteristics	Type I	Type II	Type III
Prevalence	70%-80%	5%-10%	10%-20%
Background	Autoimmune chronic atrophic gastritis	Gastrinomas (Zollinger-Ellison syndrome)	Normal mucosa
Number of lesions	Multiple	Multiple	Single
Size of tumors	1-2 cm	1 cm	> 2 cm
Site of tumor	Corpus and/or fundus	Corpus and/or fundus	Anywhere
Serum gastrin levels	Elevated	Elevated	Normal
Gastric pH	High	Low	Normal
Invasion	Rare	More common	Common
Prognosis (5-yr survival)	Excellent (90%-95%)	Good (70%-90%)	Worse (less than 35%)