Prevalence and factors associated with vitamin C deficiency in inflammatory bowel disease

Table 3 Clinical features of vitamin C deficiency

	Vitamin C deficiency (n = 65)	Normal vitamin C level (n = 236)	P value
Presence of ≥ 1 clinical feature(s) of scurvy	43 (66.2%)	138 (58.5%)	0.3
None	22 (33.8%)	98 (41.5%)	-
Fatigue	28 (43.1%)	65 (27.5%)	0.021
Arthritis/arthralgias	27 (41.5%)	96 (40.7%)	0.9
Skin findings (rash, hyperpigmentation)	9 (13.8%)	29 (12.3%)	0.7
Easy bruising	6 (9.2%)	9 (3.8%)	0.1
Gingivitis	3 (4.6%)	6 (2.5%)	0.4
Poor wound healing	3 (4.6%)	1 (0.4%)	0.031
Perifollicular findings (hemorrhage, folliculitis)	2 (3.1%)	1 (0.4%)	0.1
Alopecia	1 (1.5%)	5 (2.1%)	1.0

¹Patients with vitamin C deficiency were more likely to report fatigue and poor wound healing.

There was no difference in presence of clinical features of scurvy between patients with vitamin C deficiency and those without.