Liver Imaging Reporting and Data System criteria for the diagnosis of hepatocellular carcinoma in clinical practice: A pictorial minireview

Figure 3 A 47 mm liver mass was incidentally found, in a 40-year-old man with beta thalassemia, during cardiac magnetic resonance investigation for myocardial iron overload. A-C: On abdominal magnetic resonance imaging, the lesion demonstrated high signal intensity on T2 weighted image (A), arterial phase hyperenhancement on post-contrast arterial phase (B), and washout on portal phase (C). Although there are no current evidence-based guidelines for patients with beta thalassemia without cirrhosis, the hepatologist confirmed the patient’s risk status and proposed that Liver Imaging Reporting and Data System (LI-RADS) should be applied. According to the LI-RADS criteria, the lesion was categorized as LR-5 (definite hepatocellular carcinoma); D: Unenhanced computed tomography scan after transarterial chemoembolization showed accumulation of iodized oil (arrow) within the tumor.