©The Author(s) 2022.
World J Gastroenterol. Aug 21, 2022; 28(31): 4235-4248
Published online Aug 21, 2022. doi: 10.3748/wjg.v28.i31.4235
Published online Aug 21, 2022. doi: 10.3748/wjg.v28.i31.4235
Table 2 Pancreatic juice and cyst fluid biomarkers, saliva biomarkers, urine biomarkers
| Pancreatic juice and cyst fluid biomarkers | |||
| Mutant genes | Mucins | Interleukins | Methylated DNA markers |
| GNAS | MUC4 | IL-1b | C13orf18 |
| KRAS | MUC16 | IL-5 | FER1L4 |
| TP53 | MUC5AC | IL-8 | BMP3 |
| SMAD4 | |||
| PIK3CA | |||
| PTEN | |||
| AKT1 | |||
| Saliva biomarkers | |||
| Upregulated genes | Downregulated genes | LncRNA | |
| MBD3L2 | TK2 | HOTAIR | |
| KRAS | GLTSCR2 | PVT1 | |
| STIM2 | CDKL3 | ||
| DMXL2 | TPT1 | ||
| ACRV1 | DPM1 | ||
| DMD | |||
| CABLES1 | |||
| Urine biomarkers | |||
| Protein markers | MiRNA | Metabolites | |
| REG1A | miR-143 | CA19.9 | |
| TFF1 | miR-204 | Proline | |
| LYVE1 | miR-223 | Sphingomyelin (d18:2, C17:0) | |
| miR-30e | Phosphatidylcholine | ||
| Isocitrate | |||
| Sphinganine-1-phosphate | |||
| Histidine | |||
| Pyruvate | |||
| Sphingomyelin (d17:1, C18:0) | |||
- Citation: Tonini V, Zanni M. Early diagnosis of pancreatic cancer: What strategies to avoid a foretold catastrophe. World J Gastroenterol 2022; 28(31): 4235-4248
- URL: https://www.wjgnet.com/1007-9327/full/v28/i31/4235.htm
- DOI: https://dx.doi.org/10.3748/wjg.v28.i31.4235