Eliminating viral hepatitis in children after liver transplants: How to reach the goal by 2030

Table 1 Risk factors of de novo hepatitis B infection in children after liver transplantation

Risk factors
Positive anti-HBc donor[40]
Positive-intrahepatic HBV DNA[40]
Liver graft HBV DNA > 1000 copies[40]
Intraoperative fresh-frozen plasma transfusion > 400 mL[40]
Positive-anti-HBc recipients[40]
Pre-operative anti-HBs < 1000 mIU/mL[40,43,48]
Post-operative anti-HBs < 100-200 mIU/mL[48,53]
Hepatitis B surface mutation (within the “a” determinant region[54])

Anti-HBc: Hepatitis B core antibody; anti-HBs: Hepatitis B surface antibody.