Structure of the myenteric plexus in normal and diseased human ileum analyzed by X-ray virtual histology slices

Table 2 Experimental and reconstruction parameters

Scan configuration	Effective pixel size (µm)	Energy (keV)	Number of projections1	Phase retrieval scheme	Phase retrieval parameter	Ring removal algorithm
Laboratory setup (liquid metal jet)	0.9202	9.25 (Kα)	1 × 1000 (50 s) or 1 × 700 (40 s)	BAC	α = 0.008, β = 0.160	Wavelet
Laboratory setup (rotating anode)	1.072	8.05 (Kα)	1 × 1000 (50 s) or 1 × 700 (40 s)	BAC	α = 0.07, β = 0.16	Wavelet
GINIX waveguide (all samples except for ED/Ehlers-Danlos patient)	0.169	8.00	4 × 1500 (1 s) or 3 × 1500 (1 s)	Non-linear Tikhonov3	δ/β = 50, lim1 = 8e-3, lim2 = 0.5	Additive
GINIX waveguide (ED/Ehlers-Danlos patient)	0.176	7.50	4 × 1000 (2 s)	Non-linear Tikhonov3	δ/β = 50, lim1 = 1e-4, lim2 = 0.1	Additive

¹Due to time constraints, some samples were scanned with a lower number of projections and shorter exposure times (in the overview scans) or with less distances (in the high-resolution scans of the drug-induced chronic intestinal pseudo-obstruction patient and of the 40 years old control).

²After voxel binning of 2 × 2 × 2.

³No support, no restriction on phase shift.

GINIX: Gottingen Instrument for Nano-Imaging with X-rays; ED: Enteric dysmotility.