Review
Copyright ©The Author(s) 2022.
World J Gastroenterol. Jul 14, 2022; 28(26): 3008-3026
Published online Jul 14, 2022. doi: 10.3748/wjg.v28.i26.3008
Table 1 World Health Organization Classification and grading criteria for neuroendocrine neoplasms of the gastrointestinal tract and hepatopancreatobiliary organs (7)
Terminology
Differentiation
Grade
Mitoses/2 mm2
Ki-67 index
NEN grade 1Well differentiatedLow< 2< 3%
NEN grade 2Intermediate2-203%-20%
NEN grade 3High> 20> 20%
SCNECPoorly differentiatedHigh1> 20> 20%
LCNEC> 20> 20%
MiNENWell or poorly differentiatedVariableVariableVariable