Upregulated adenosine 2A receptor accelerates post-infectious irritable bowel syndrome by promoting CD4+ T cells’ T helper 17 polarization

Table 3 The effect of adenosine 2A receptor on the abdominal withdrawal reflex score in the post-infectious irritable bowel syndrome mouse

Distending air volume (mL)	AWR
	0.25	0.35	0.5	0.65
Control (n = 6)	0.00 ± 0.00	1.67 ± 0.53	2.56 ± 0.62	3.67 ± 0.57
PI-IBS (n = 6)	0.00 ± 0.00	2.11 ± 0.49a	3.22 ± 0.58	3.89 ± 0.46
IBS + Sch58261 (n = 6)	0.00 ± 0.00	1.89 ± 0.40c	2.89 ± 0.45	3.67 ± 0.52
IBS + CGS21680 (n = 6)	0.00 ± 0.00	2.00 ± 0.41	3.11 ± 0.54	3.78 ± 0.57

^aP < 0.05 vs control group.

^cP < 0.05 vs post-infectious irritable bowel syndrome group. AWR: Abdominal withdrawal reflex; PI-IBS: Post-infectious irritable bowel syndrome.