Fecal gene detection based on next generation sequencing for colorectal cancer diagnosis

doi:10.3748/wjg.v28.i25.2920

Advanced Search

BPG is committed to discovery and dissemination of knowledge

Home / Archive / Volume 28, Issue 25

This Article

(190)

(197)

(0)

(11)

(1)

(4683)

(6)

Peer-Review Report of This Article

CrossCheck and Google Search of This Article

Academic Rules and Norms of This Article

Citation of this article

Corresponding Author of This Article

Research Domain of This Article

Article-Type of This Article

Open-Access Policy of This Article

Times Cited Counts in Google of This Article

Journal Information of This Article

Publication Name

World Journal of Gastroenterology

ISSN

1007-9327

Publisher of This Article

Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

- Full Article with Cover (PDF)
- Full Article (XML)

Basic Study

World J Gastroenterol. Jul 7, 2022; 28(25): 2920-2936
Published online Jul 7, 2022. doi: 10.3748/wjg.v28.i25.2920

Table 5 Comparison of pathogenic mutation sites in preoperative stools vs tumor tissues

Gene	Positive rate of pathogenic gene mutation sites
Gene	Preoperative feces	Tumor tissues
TP53	37.04% (10/27)	46.00% (23/50)
APC	11.11% (3/27)	18.00% (9/50)
KRAS	25.93% (7/27)	54.00% (27/50)
PIK3CA	3.70% (1/27)	22.00% (11/50)
FBXW7	3.70% (1/27)	6.00% (3/50)
GNAS	3.70% (1/27)	4.00% (2/50)
PTEN	3.70% (1/27)	0
ABL1	3.70% (1/27)	0
PDGFRA	3.70% (1/27)	0
ATM	0	2.00% (1/50)
SMAD4	0	2.00% (1/50)
BRAF	0	2.00% (1/50)
PTPN11	0	2.00% (1/50)
NRAS	0	2.00% (1/50)
CTNNB1	0	2.00% (1/50)
VHL	3.70% (1/27)	0

Positive rate of pathogenic gene mutation site: The number of people with mutations corresponding to the pathogenic mutation sites of any gene/total number of samples.

Full Size Table

Citation: He SY, Li YC, Wang Y, Peng HL, Zhou CL, Zhang CM, Chen SL, Yin JF, Lin M. Fecal gene detection based on next generation sequencing for colorectal cancer diagnosis. World J Gastroenterol 2022; 28(25): 2920-2936
URL: https://www.wjgnet.com/1007-9327/full/v28/i25/2920.htm
DOI: https://dx.doi.org/10.3748/wjg.v28.i25.2920

He SY, Li YC, Wang Y, Peng HL, Zhou CL, Zhang CM, Chen SL, Yin JF, Lin M. Fecal gene detection based on next generation sequencing for colorectal cancer diagnosis. World J Gastroenterol 2022; 28(25): 2920-2936 [PMID: 35978873 DOI: 10.3748/wjg.v28.i25.2920]

All content on this site: Copyright © 1993-2026 Baishideng Publishing Group Inc, its licensors, and contributors. All rights are reserved, including those for text and data mining, AI training, and similar technologies. For all open access content, the relevant licensing terms apply.