Whole lesion histogram analysis of apparent diffusion coefficient predicts therapy response in locally advanced rectal cancer

doi:10.3748/wjg.v28.i23.2609

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Jun 21, 2022; 28(23): 2609-2624
Published online Jun 21, 2022. doi: 10.3748/wjg.v28.i23.2609

Table 6 Intraobserver variability

		ICC	95%CI
Basal
Test1 and test2, reader1	ROI ADCmean	0.850	0.742–0.800
Test1 and test2, reader2	ROI ADCmean	0.890	0.850-0.820
After treatment
Test1 and test2, reader1	ROI ADCmean	0.800	0.750-0.819
Test1 and test2, reader2	ROI ADCmean	0.823	0.800-0.850
Basal
Test1 and test2, reader1	ADCmean	0.850	0.756-0.920
Test1 and test2, reader2	ADCmean	0.777	0.745-0.812
After treatment
Test1 and test2, reader1	ADCmean	0.845	0.830-0.850
Test1 and test2, reader2	ADCmean	0.823	0.800-0.833
Basal
Test1 and test2, reader1	10^th percentile	0.820	0.880-0.950
Test1 and test2, reader2	10^th percentile	0.880	0.800-0.920
After treatment
Test1 and test2, reader1	10^th percentile	0.780	0.740-0.853
Test1 and test2, reader2	10^th percentile	0.853	0.723-0.901
Basal
Test1 and test2, reader1	25^th percentile	0.803	0.800-0.922
Test1 and test2, reader2	25^th percentile	0.863	0.801-0.895
After treatment
Test1 and test2, reader1	25^th percentile	0.788	0.750-0.837
Test1 and test2, reader2	25^th percentile	0.820	0.780-0.846
Basal
Test1 and test2, reader1	50^th percentile	0.850	0.840-0.920
Test1 and test2, reader2	50^th percentile	0.845	0.790-0.860
After treatment
Test1 and test2, reader1	50^th percentile	0.821	0.800-0.913
Test1 and test2, reader2	50^th percentile	0.833	0.800-0.897
Basal
Test1 and test2, reader1	75^th percentile	0.821	0.790-0.860
Test1 and test2, reader2	75^th percentile	0.859	0.820-0.920
After treatment
Test1 and test2, reader1	75^th percentile	0.851	0.790-0.880
Test1 and test2, reader2	75^th percentile	0.837	0.791-0.856
Basal
Test1 and test2, reader1	90^th percentile	0.850	0.820-0.890
Test1 and test2, reader2	90^th percentile	0.880	0.850-0.960
After treatment
Test1 and test2, reader1	90^th percentile	0.831	0.800-0.902
Test1 and test2, reader2	90^th percentile	0.901	0.850-0.975
Basal
Test1 and test2, reader1	Skewness	0.920	0.900-0.940
Test1 and test2, reader2	Skewness	0.901	0.880-0.923
After treatment
Test1 and test2, reader1	Skewness	0.931	0.920-0.950
Test1 and test2, reader2	Skewness	0.889	0.877-0.910
Basal
Test1 and test2, reader1	Kurtosis	0.920	0.890-0.950
Test1 and test2, reader2	Kurtosis	0.910	0.850-0.960
After treatment
Test1 and test2, reader1	Kurtosis	0.890	0.850-0.960
Test1 and test2, reader2	Kurtosis	0.880	0.840-0.982

ADC: Apparent diffusion coefficient; ICC: Intraclass correlation coefficient; ROI: Region of interest.

Citation: Jiménez de los Santos ME, Reyes-Pérez JA, Domínguez Osorio V, Villaseñor-Navarro Y, Moreno-Astudillo L, Vela-Sarmiento I, Sollozo-Dupont I. Whole lesion histogram analysis of apparent diffusion coefficient predicts therapy response in locally advanced rectal cancer. World J Gastroenterol 2022; 28(23): 2609-2624
URL: https://www.wjgnet.com/1007-9327/full/v28/i23/2609.htm
DOI: https://dx.doi.org/10.3748/wjg.v28.i23.2609