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Copyright ©The Author(s) 2022.
World J Gastroenterol. Jan 14, 2022; 28(2): 188-198
Published online Jan 14, 2022. doi: 10.3748/wjg.v28.i2.188
Figure 3
Figure 3 Multi-localization and functional diversity of protein kinase Cδ. Protein kinase Cδ (PKCδ) resides at various locations, including the cytosol, nucleus, estrogen receptor (ER), mitochondria, Golgi, extracellular space, and plasma membrane (inside and outside the cell). At each location, PKCδ acts as an apoptotic or survival factor in response to various stimuli, such as genotoxic stresses, phorbol ester, DNA damage, ER stress, tumor necrosis factor (TNF)-α, and TNF-related apoptosis-inducing ligand. PKCδ: Protein kinase Cδ; ER: Estrogen receptor; PM: Plasma membrane.