Clinical utility of two-dimensional shear-wave elastography in monitoring disease course in autoimmune hepatitis-primary biliary cholangitis overlap syndrome

Table 4 Baseline characteristics of the patients between patients with complete biochemical remission and without biochemical remission

Characteristic	Without biochemical remission (n = 46)	Complete biochemical remission (n = 36)	P value
Sex, female, n (%)	39 (90)	35 (97.2)	0.07
Age, yr	50 (43-54)	49 (44-55)	0.99
BMI (kg/m2)	21.1 (19.4-22.4)	21.9 (20.0-23.0)	0.27
TB, μmol/L	38.7 (27.4-61.2)	19.6 (15.5-43.6)	0.009
ALB, g/L	39.7 (34.8-45.3)	41 (35.5-44.8)	0.56
PLT, × 109/L	126 (90-170)	150 (85-215)	0.18
ALT, IU/L	98 (71-136)	146 (50-215.3)	0.17
AST, IU/L	111 (82-153)	126 (68-247)	0.63
ALP, IU/L	417 (297-533)	217 (143-412)	0.0005
GGT, IU/L	419 (269-558)	289 (111-451)	0.005
IgG, g/L	19.2 (15.3-22.3)	21.9 (16.5-26.2)	0.06
IgM, g/L	3500 (2400-4830)	3290 (2245-5925)	0.86
Fibrosis stage, n			0.19
S0-S1	4	9
S2	19	14
S3	6	2
S4	17	11
Activity grad, n			0.29
G0-G1	1	1
G2	19	8
G3	24	26
G4	2	1
LS, kPa	12.9 (10.0-17.0)	11.3 (7.7-15.4)	0.14

Data are presented as median and interquartile range, number (percentage). The reference laboratory parameter value: Total bilirubin: 5-28 μmol/L; alanine aminotransferase < 50 IU/L; aspartate aminotransferase < 40 IU/L; albumin: 40-55 g/L; platelet count: 100-300 × 10⁹/L; alkaline phosphatase: 51-160 IU/L; gamma-glutamyl transpeptidase: < 60 IU/L; immunoglobulin G: 8-15.5 g/L; immunoglobulin M: 700-2200 mg/L. BMI: Body mass index; TB: Total bilirubin; ALB: Albumin; PLT: Platelet count; ALT: Alanine aminotransferase; AST: Aspartate aminotransferase; ALP: Alkaline phosphatase; GGT: Gamma-glutamyl transpeptidase; IgG: Immunoglobulin G; IgM: Immunoglobulin M; LS: Liver stiffness.