Sinapic acid ameliorates D-galactosamine/lipopolysaccharide-induced fulminant hepatitis in rats: Role of nuclear factor erythroid-related factor 2/heme oxygenase-1 pathways

doi:10.3748/wjg.v27.i7.592

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Feb 21, 2021; 27(7): 592-608
Published online Feb 21, 2021. doi: 10.3748/wjg.v27.i7.592

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Figure 8 Graphical abstract. SA: Sinapic acid; D-GalN/LPS: D-galactosamine/lipopolysaccharide; ALT: Alanine transaminase; AST: Aspartate aminotransferase; TNF-α: Tumor necrosis factor-α; IL-6: Interleukin 6; TGF-β1: Transforming growth factor-β1; HO-1: Heme oxygenase-1; Nrf2: Nuclear factor erythroid 2-related factor 2; IkBα: Nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor alpha; NF-κb: Nuclear factor kappa B; ROS: Reactive oxygen species; CAT: Catalase; MDA: Malondialdehyde; GPX: Glutathione peroxidase; SOD: Superoxide dismutase.

Citation: Ansari MA, Raish M, Bin Jardan YA, Ahmad A, Shahid M, Ahmad SF, Haq N, Khan MR, Bakheet SA. Sinapic acid ameliorates D-galactosamine/lipopolysaccharide-induced fulminant hepatitis in rats: Role of nuclear factor erythroid-related factor 2/heme oxygenase-1 pathways. World J Gastroenterol 2021; 27(7): 592-608
URL: https://www.wjgnet.com/1007-9327/full/v27/i7/592.htm
DOI: https://dx.doi.org/10.3748/wjg.v27.i7.592