Sinapic acid ameliorates D-galactosamine/lipopolysaccharide-induced fulminant hepatitis in rats: Role of nuclear factor erythroid-related factor 2/heme oxygenase-1 pathways

doi:10.3748/wjg.v27.i7.592

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Feb 21, 2021; 27(7): 592-608
Published online Feb 21, 2021. doi: 10.3748/wjg.v27.i7.592

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Figure 4 Effect of sinapic acid pretreatment on cytokines and inflammatory markers in hepatic tissue of D-galactosamine/lipopolysaccharide-induced acute liver failure. The results are presented as mean ± SE with six animals per group. ^aDenotes significant differences compared to the control group (P < 0.05); ^bdenotes significant differences compared to the D-galactosamine/lipopolysaccharide group (P < 0.05). TNF-α: Tumor necrosis factor-α; IL-6: Interleukin 6; MPO: Myeloperoxidase; SA: Sinapic acid; D-GalN/LPS: D-galactosamine/lipopolysaccharide.

Citation: Ansari MA, Raish M, Bin Jardan YA, Ahmad A, Shahid M, Ahmad SF, Haq N, Khan MR, Bakheet SA. Sinapic acid ameliorates D-galactosamine/lipopolysaccharide-induced fulminant hepatitis in rats: Role of nuclear factor erythroid-related factor 2/heme oxygenase-1 pathways. World J Gastroenterol 2021; 27(7): 592-608
URL: https://www.wjgnet.com/1007-9327/full/v27/i7/592.htm
DOI: https://dx.doi.org/10.3748/wjg.v27.i7.592