Xiangbinfang granules enhance gastric antrum motility via intramuscular interstitial cells of Cajal in mice

Figure 3 Effect of Xiangbinfang granule on gastric antrum slow wave in wild-type and W/W^v mice. A: Representative trace of the effect of different concentrations of Champaign formula on gastric antrum slow waves in wild-type (WT) mice. After infusion of Xiangbinfang granule (XBF) at the concentration of 10^-2 g/L (Aa), 5 × 10^-2 g/L (Ab) and 10^-1 g/L (Ac), the slow waves resting membrane potential (RMP) decreased, frequency increased and amplitude decreased; B: Representative trace of the effect of different concentrations of Champaign formula on gastric antrum slow waves in W/W^v mice. Infused XBF at the concentrations of 10^-2 g/L (Ba), 5 × 10^-2 g/L (Bb) and 10^-1 g/L (Bc) decreased the RMP in W/W^v gastric antrum slow waves; C-E: Histogram of XBF for gastric slow wave RMP (C), frequency (D) and amplitude (E) in WT and W/W^v mice. (Control, n = 18; treatment, n = 6. Paired t-test was used to compare the difference before and after administration, ^aP < 0.05, ^bP < 0.001, ^cP < 0.0001). WT: Wild type; XBF: Xiangbinfang granule.