Clinicopathological features and prognostic factors associated with gastroenteropancreatic mixed neuroendocrine non-neuroendocrine neoplasms in Chinese patients

Table 5 Comparison between patients with mixed neuroendocrine-non-neuroendocrine neoplasms and those with poorly differentiated adenocarcinoma

Variable	Poorly differentiated adenocarcinoma (n = 58)	MiNEN (n = 46)	P value
Male/female	37/21	34/12	0.271
Mean age, years, (range)	61 (31-81)	65 (41-84)	0.055
Location			0.836
Stomach	42	35
Intestine	12	9
Pancreas	4	2
Size (cm)			0.254
< 5	25	25
≥ 5	33	21
Ki- 67 index			0.104
< 50%	13	17
≥ 50%	45	29
Lymph node metastasis			0.385
Presence	47	34
Absence	11	12
Distant metastasis			0.750
Presence	16	14
Absence	42	32
Clinical TNM stage			0.402
I + II	10	13
III	34	23
IV	14	10
Survival time (mo)			0.453
Median	18	30
Mean	24.3	28.6
Follow-up			0.863
Dead	33	27
Alive	17	15

MiNEN: Mixed neuroendocrine-non-neuroendocrine neoplasms; TNM: Tumor node metastasis.