Observational Study
Copyright ©The Author(s) 2021.
World J Gastroenterol. Dec 7, 2021; 27(45): 7813-7830
Published online Dec 7, 2021. doi: 10.3748/wjg.v27.i45.7813
Table 1 Histopathological and perioperative details of resectable gallbladder patients (n = 172)
Patient characteristic
n (%)
Type of surgery
Wedge resection93 (54)
Anatomical segment IVb/V resection66 (38.4)
Modified extended right hepatectomy12 (7)
Lap cholecystectomy1 (0.6)
Histology
Adenocarcinoma160 (93)
Adenosquamous9 (5.2)
Carcinosarcoma2 (1.2)
Squamous1 (0.6)
Histological grade
Well differentiated33 (19.2)
Moderately differentiated116 (67.4)
Poorly differentiated23 (13.4)
pT stage
T125 (14.5)
T270 (40.7)
T373 (42.4)
T44 (2.4)
pN stage
N0117 (68)
N+55 (32)
LVI positive54 (31.4)
PNI positive56 (32.5)
IAC positive15 (8.7)
R0/R1 resection
R0161 (93.6)
R111 (6.4) [liver (n = 4), cystic duct (n = 4), bile duct (n = 3)]
Final stage (AJCC 8th)
I21 (12.2)
II45 (26.2)
III73 (42.4)
IV33 (19.2)
Postoperative morbidity
Overall53 (30.8)
Clavien-Dindo grade III & above21 (12.2)
Bile leak14 (8.1)
Clinically significant5 (2.9)
90 d mortality8 (4.6)
Adjuvant therapy117/147 (79.6)
Chemotherapy only80
Chemoradiotherapy37
Advised but not taken/incomplete30
Not indicated25