Overview of the microbiota in the gut-liver axis in viral B and C hepatitis

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Nov 21, 2021; 27(43): 7446-7461
Published online Nov 21, 2021. doi: 10.3748/wjg.v27.i43.7446

Table 2 Microbial changes as a result of several treatments in viral B and C hepatitis

Drug	Type of study	Changes in gut microbiota	Ref.
Entecavir	Experimental (mice)	↑ Lachnospiraceae, Akkermansia, Alistipes, Escherichia, Shigella, Oscillibacter, Bilophila	Li et al[127]
Entecavir	Clinical	↑ Clostridium sensu stricto 1, Erysipelotrichaceae UCG-007, Intestinibacter; ↓ Streptococcus, Atopobium, and Murdochiella	Lu et al[128]
Direct antiviral agents in patients with HCV infection	Clinical	↑ Phylum Firmicutes, genera Lachnospira	Pérez-Matute et al[129]
Direct antiviral agents in patients with HCV-related liver cirrhosis	Clinical	↓ Enterobacteriaceae, Staphylococcus and Veillonellaceae	Ponziani et al[130]

HCV: Hepatitis C virus.

Citation: Neag MA, Mitre AO, Catinean A, Buzoianu AD. Overview of the microbiota in the gut-liver axis in viral B and C hepatitis. World J Gastroenterol 2021; 27(43): 7446-7461
URL: https://www.wjgnet.com/1007-9327/full/v27/i43/7446.htm
DOI: https://dx.doi.org/10.3748/wjg.v27.i43.7446

Neag MA, Mitre AO, Catinean A, Buzoianu AD. Overview of the microbiota in the gut-liver axis in viral B and C hepatitis. World J Gastroenterol 2021; 27(43): 7446-7461 [PMID: 34887642 DOI: 10.3748/wjg.v27.i43.7446]

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