Cross-sectional evaluation of circulating hepatitis B virus RNA and DNA: Different quasispecies?

doi:10.3748/wjg.v27.i41.7144

Advanced Search

BPG is committed to discovery and dissemination of knowledge

Home / Archive / Volume 27, Issue 41

This Article

Academic Content and Language Evaluation of This Article

Academic Rules and Norms of This Article

Supplementary Materials of This Article

Citation of this article

Corresponding Author of This Article

Research Domain of This Article

Article-Type of This Article

Open-Access Policy of This Article

Times Cited Counts in Google of This Article

Number of Hits and Downloads for This Article

Total Article Views (4741)

All Articles published online

The chart showing PDF series, WORD series, HTML series, Figures (1-6) series, Tables (1-1) series.

Item

Count

PDF

313

WORD

110

HTML

2576

Figures (1-6)

187

Tables (1-1)

184

Sum=3370

Featured Article

The chart showing Browse series, Download series.

Item

Count

Browse

307

Download

361

Sum=668

Publishing Process of This Article

Item

Count

Browse

292

Download

411

Sum=703

Nov 7, 2021 (publication date) through Jun 17, 2024

Times Cited of This Article

Times Cited (2)

Journal Information of This Article

Publication Name

World Journal of Gastroenterology

ISSN

1007-9327

Publisher of This Article

Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Basic Study

World J Gastroenterol. Nov 7, 2021; 27(41): 7144-7158
Published online Nov 7, 2021. doi: 10.3748/wjg.v27.i41.7144

Table 1 Clinical and viral characteristics of chronic hepatitis B patients enrolled in the study

	Total, n = 13
Age, yr, median (IQR)	41.35 (31.7-47.2)
Male, n (%)	11 (84.6)
Genotype, n (%)
A	3 (23.1)
C	3 (23.1)
D	2 (15.4)
E	2 (15.4)
F	3 (23.1)
ALT, IU/L, median (IQR)	124 (66-160)
HBeAg +ve, n (%)	11 (84.6)
HBV DNA, Log₁₀IU/mL, median (IQR)	8 (8-8.43)
HBV RNA, Log₁₀ copies/mL, median (IQR)	5.18 (4.94-6.02)
Fibrosis, n (%)¹
Nonsignificant	8 (61.64)
Significant	3 (23.08)
Cirrhosis, n (%)	2 (15.39)

¹Nonsignificant fibrosis indicates Ishak fibrosis stage < 3, significant fibrosis F ≥ 3 and < 5, and cirrhosis F5-6. Nonsignificant fibrosis by noninvasive markers indicates liver stiffness < 7-8.5 kPa, significant fibrosis > 7-8.5 and < 11-14 kPa and cirrhosis > 11-14 kPa by transient elastography according to World Health Organization Guidelines for the prevention, care and treatment of persons with chronic hepatitis B infection criteria[20].

F: Fibrosis; IQR: Interquartile range; ALT: Alanine aminotransferase; HBeAg +ve: Hepatitis B e-antigen positive; HBsAg: Hepatitis B virus surface antigen; HBV: Hepatitis B virus.

Citation: Garcia-Garcia S, Cortese MF, Tabernero D, Gregori J, Vila M, Pacín B, Quer J, Casillas R, Castillo-Ribelles L, Ferrer-Costa R, Rando-Segura A, Trejo-Zahínos J, Pumarola T, Casis E, Esteban R, Riveiro-Barciela M, Buti M, Rodríguez-Frías F. Cross-sectional evaluation of circulating hepatitis B virus RNA and DNA: Different quasispecies? World J Gastroenterol 2021; 27(41): 7144-7158
URL: https://www.wjgnet.com/1007-9327/full/v27/i41/7144.htm
DOI: https://dx.doi.org/10.3748/wjg.v27.i41.7144