Could saline irrigation clear all residual common bile duct stones after lithotripsy? A self-controlled prospective cohort study

Table 3 Biliary cleanliness before and after saline irrigation, assessed by logistic regression analysis

		Residual massive stones (score = 1) before saline irrigation					Biliary clearance (score = 5) after 100 mL saline irrigation
	n/N	Univariable analysis	Multivariable analysis	n/N	Univariable analysis	Multivariable analysis
		OR (95%CI)	P value	OR (95%CI)	P value		OR (95%CI)	P value	OR (95%CI)	P value
Age
≤ 65 yr	6/27	1.00		19/27		19/27	1.00		-
> 65 yr	7/20	1.89 (0.52-6.86)	0.34	13/20		13/20	0.78 (0.23-2.69)	0.70	-	-
Gender					-
Female	9/24	1.00		16/24		16/24	1.00		-
Male	4/23	0.35 (0.09-1.37)	0.13	16/23	0.17	16/23	1.14 (0.34-3.90)	0.83	-	-
CBD diameter
≤ 15 mm	5/32	1.00		26/32		26/32	1.00		1.00
> 15 mm	8/15	6.17 (1.53-24.84)	0.01	6/15	0.034	6/15	0.15 (0.04-0.60)	0.007	0.08 (0.01-0.49)	0.007
Stone number
Single	3/11	1.00		10/11		10/11	1.00		1.00
Multiple	10/36	1.03 (0.23-4.66)	0.97	22/36	-	22/36	0.16 (0.02-1.37)	0.09	0.08 (0.01-1.09)	0.06
Stone diameter
≤ 15 mm	8/36	1.00		26/36		26/36	1.00		-
> 15 mm	5/11	2.92 (0.70-12.11)	0.14	6/11	0.34	6/11	0.46 (0.12-1.86)	0.28	-	-
Pigment-based stones
No	4/17	1.00		14/17		14/17	1.00		1.00
Yes	9/30	1.39 (0.36-5.46)	0.63	18/30	-	18/30	0.32 (0.08-1.36)	0.12	0.43 (0.05-3.60)	0.44
PAD
No	4/15	1.00		26/32		26/32	1.00		1.00
Yes	9/32	1.08 (0.27-4.28)	0.92	6/15	-	6/15	6.50 (1.67-25.38)	0.007	6.51 (1.08-39.21)	0.041

N: Total number; CBD: Common bile duct; PAD: Periampullary diverticula; CI: Confidence interval; OR: Odds ratio.