Diagnostic usefulness of selected proteases and acute phase factors in patients with colorectal adenocarcinoma

Table 3 Characteristics of biochemical parameters in patients' blood serum in relation to the severity according to the Dukes’ classification

No.	Biochemical parameters tested	Groups	A	B	C	D	K	Significance level P value
1	CB, mU/L	M	19.9	15.4	16.8	15.5	11.4	NS
		n	22	52	72	39	35
		SD	19.3	9.4	8.4	7.6	6.5
2	LE, µg/L	M	386.1	929.9	602.1	1129.5	379.1	< 0.001
		n	5	16	15	15	30
		SD	190.2	637.5	389.6	651.7	187.3
3	TSA, mg%	M	67.8	100.8	92.9	107.2	71.4	< 0.001
		n	6	21	24	20	31
		SD	7.4	39.3	25.1	26.3	15.1
4	LASA, mg%	M	0.44	0.8	0.6	0.6	0.7	NS
		n	6	21	24	21	37
		SD	0.12	0.51	0.23	0.20	0.31
5	ATA, U/mL	M	3100.0	2925.0	3152.1	3576.2	2015.9	< 0.010
		n	2	21	24	21	29
		SD	424.3	1294.5	1684.7	1548.8	689.6

Dukes’ classification system for colorectal cancer: A, B, C, D: All patients with colorectal adenocarcinoma; ATA: Antitrypsin activity; CB: Cathepsin B; K: Control group; LASA: Lipid-bound sialic acid; LE: Leukocytic elastase; M: Mean value; NS: Not significant; TSA: Total sialic acid.