Validation of the Italian translation of the perceived stigma scale and resilience assessment in inflammatory bowel disease patients

Table 2 Demographic and clinical characteristics of the validating cohort

	Overall (n = 126)	CD (n = 57)	UC (n = 69)	P value
Age (mean ± SD)	46.13 (± 16.95)	42.29 (± 15.7)	49.29 (± 17.38)	0.03
Male	71 (56.4%)	33 (57.9%)	38 (55.1%)	0.86
BMI	23.9 (± 4.1)	23.9 (± 4.3)	23.9 (± 3.9)	0.67
Disease duration (median, IQR)	8 (3-16)	10 (3-17)	8 (3.5-13)	0.44
Disease characteristics (CD)
Location (CD)	-		-
Terminal ileum (L1)		13 (22.8%)
Colon (L2)		8 (14.0%)
Ileo-colon (L3)		28 (49.1%)
Upper GI (L4)		2 (3.5%)
Perianal disease (p)		19 (33.3%)
Behavior (CD)	-	-
Inflammatory (B1)		32 (56.1%)
Stricturing (B2)		25 (43.9%)
Penetrating (B3)		16 (28.1%)
Disease activity (HBI)	-	-
< 5		38 (66.7%)
5-7		14 (24.6%)
8-16		5 (8.8%)
> 16	-	0 (0%)
Disease characteristics (UC)			-
Location	-	-	7 (10.1%)
Proctitis (E1)			26 (37.7%)
Left sided (E2)			36 (52.2%)
Extensive (E3)
Disease activity (pMayo)	-
< 2			45 (65.2%)
2-4			13 (18.8%)
5-7			4 (5.8%)
> 7			7 (10.1%)
Pouch			3 (4.4%)
Extraintestinal manifestations	36 (28.6%)	17 (29.8%)	19 (27.5%)	0.84
Previous abdominal surgery	38 (30.2%)	22 (38.6%)	16 (42.1%)	0.07
Calprotectin				0.54
< 50	43(34.1%)	15 (26.3%)	28 (40.6%)
51-250	33 (16.2%)	17 (29.8%)	16 (23.2.%)
> 250	16 (12.7%)	7 (12.3%)	9 (13.4%)
Missing	34 (27.0%)	18 (31.6%)	16 (23.2%)
CRP				1.00
Normal	77 (61.1)	35 (62.4%)	42 (60.9%)
Raised	39 (31.0%)	18 (31.6%)	21 (30.4%)
Missing	10 (7.9%)	4 (7.0%)	6 (8.7%)
Comorbidities	40 (31.8%)	16 (28.1%)	24 (34.8%)	0.45
Cardiomyopathy	15 (11.9%)	3 (5.26%)	12 (17.4%)	0.05
Hypertension	28 (22.2%)	12 (42.9%)	16 (23.2%)	0.83
Diabetes	11 (8.73%)	4 (7.0%)	7 (10.1%)	0.75
Hepatic failure	1 (0.8%)	1 (1.8%)	0 (0.0%)	0.45
Kidney failure	4 (3.17%)	3 (5.26%)	1 (1.45%)	0.32
Respiratory failure	2 (1.6%)	1 (1.8%)	1 (1.5%)	1.00
Neurologic diseases	5 (4.0%)	1 (1.8%)	4 (5.8%)	0.37
Psychiatric disorder	15 (11.9%)	7 (12.3%)	8 (11.6%)	1.00
Onco-hematological diseases	12 (9.5%)	2 (3.5%)	10 (14.5%)	0.06

BMI: Body mass index; CD: Crohn’s disease; CRP: C-reactive protein; GI: Gastrointestinal; HBI: Harvey-Bradshaw Index; IQR: Interquartile range; PMS: Partial Mayo Score; SD: Standard deviation; UC: Ulcerative colitis.