Modulation of cell physiology under hypoxia in pancreatic cancer

doi:10.3748/wjg.v27.i28.4582

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Jul 28, 2021 (publication date) through Apr 24, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Jul 28, 2021; 27(28): 4582-4602
Published online Jul 28, 2021. doi: 10.3748/wjg.v27.i28.4582

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Figure 4 Hallmarks of hypoxia in pancreatic cancer. The figure summarizes the major adaptive features of pancreatic tumor cells in response to hypoxia. In general, low O₂ availability worsens the prognosis of pancreatic cancer by promoting increases in tumor progression, drug resistance, immune evasion, and metastatic ability. Created with BioRender.com. ECM: Extracellular matrix; PSC: Pancreatic stellate cells.

Citation: Estaras M, Gonzalez A. Modulation of cell physiology under hypoxia in pancreatic cancer. World J Gastroenterol 2021; 27(28): 4582-4602
URL: https://www.wjgnet.com/1007-9327/full/v27/i28/4582.htm
DOI: https://dx.doi.org/10.3748/wjg.v27.i28.4582