Diverse expression patterns of mucin 2 in colorectal cancer indicates its mechanism related to the intestinal mucosal barrier

Table 4 Relationship between serum levels of mucin 2, diamine oxide, and D-lactate in patients with colorectal cancer (cases)

MUC2	DAO		D-LAC
	Low	High	Low	High
Low	15	8	16	7
High	17	26	15	28
χ2	3.957		7.236
P value	0.047		0.007

The measured mucin 2 (MUC2) level of P95 in the normal population was taken as the normal reference range, and those beyond P95 were regarded as increased, otherwise as decreased. Based on this, colorectal cancer patients were divided into groups with high and low levels of MUC2. Similarly, the number of cases in diamine oxide (DAO) and D-lactate (D-LAC) groups with high and low levels could be obtained. Serum MUC2 levels were positively correlated with DAO and D-LAC levels. Low: Low serum level; High: High serum level; MUC2: Mucin 2; DAO: Diamine oxide; D-LAC: D-lactate.