Stem cell injection for complex anal fistula in Crohn’s disease: A single-center experience

Table 4 Efficacy evaluation and outcomes

	1	2	3	4	5	6	7	8	9	10	11	12
Length of follow-up (mo)	27	30	8	24	26	16	12	6	8	6	6	3
Efficacy evaluation (clinical)	Complete healing	Complete healing	Complete healing	Recurrence	Persistence	Complete healing	Complete healing	Complete healing	Persistence	Complete healing	Recurrence	Complete healing
Efficacy evaluation (MRI)	Not performed	Complete healing	Not performed	Recurrence	Persistence	Not performed	Not performed	Not performed	Not performed	Persistence	Recurrence	Not performed
Time to fistula closure	6 wk	12 wk	9 wk	---	---	12 wk	30 wk	9 wk	--	9 wk	---	10 wk
Incidence of abscess during follow-up	Yes	No	No	No	Yes	No	No	No	Yes	No	Yes	No
Further surgery during follow-up	Yes; Abscess excision (twice)	No	No	Seton drainage	Yes; Abscess excision	No	No	No	Yes; Abscess excision	No	Yes; Abscess excision	No
Maintenance therapy	Adalimumab	Ustekinumab	Azathioprin	Infliximab	Ustekinumab	Vedolizumab	Ustekinumab	Ceased	Infliximab	Infliximab	Infliximab	None
Stoma reversal (if present)	No stoma	Stoma reversal	No stoma	No	No stoma	No stoma	No stoma	No stoma	No stoma	No	No	No stoma

MRI: Magnetic resonance imaging.