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©The Author(s) 2021.
World J Gastroenterol. May 21, 2021; 27(19): 2353-2365
Published online May 21, 2021. doi: 10.3748/wjg.v27.i19.2353
Published online May 21, 2021. doi: 10.3748/wjg.v27.i19.2353
Table 1 Demographic and clinical characteristics of patients with Crohn’s disease according to the presence of acute severe lower gastrointestinal bleeding
| Bleeding group (n = 75) | Non-bleeding group (n = 1359) | P value | |
| Age at diagnosis, years (median, IQR) | 23.6 (18.9-31.9) | 23.2 (18.6-33.5) | 0.952 |
| Sex, male, n (%) | 63 (84.0) | 1000 (73.6) | 0.045 |
| Disease location at diagnosis, n (%) | 0.002 | ||
| Ileum | 34 (45.3) | 377 (27.7) | |
| Colon | 1 (1.3) | 81 (6.0) | |
| Ileocolon | 40 (53.4) | 901 (66.3) | |
| Upper GI modifier at diagnosis, n (%) | 15 (20) | 355 (26.1) | 0.238 |
| Disease behavior at diagnosis, n (%) | 0.157 | ||
| Non-stricturing, non-penetrating | 59 (78.6) | 1012 (74.5) | |
| Stricturing | 11 (14.7) | 155 (11.4) | |
| Penetrating | 5 (6.7) | 192 (14.1) | |
| Perianal modifier at diagnosis, n (%) | 32 (42.7) | 686 (50.5) | 0.204 |
| Smoking status at diagnosis, n (%) | 0.540 | ||
| Never smokers | 51 (68.0) | 874 (64.3) | |
| Ex-smokers | 3 (4.0) | 99 (7.3) | |
| Current smokers | 21 (28.0) | 386 (28.4) | |
| Early use of medications, n (%) | |||
| Corticosteroids | 21 (28.0) | 399 (29.4) | 0.840 |
| Thiopurines | 10 (13.3) | 649 (47.8) | < 0.001 |
| Anti-TNF agents | 1 (1.3) | 43 (3.2) | 0.560 |
- Citation: Yoon J, Kim DS, Kim YJ, Lee JW, Hong SW, Hwang HW, Hwang SW, Park SH, Yang DH, Ye BD, Byeon JS, Myung SJ, Yang SK. Risk factors and prognostic value of acute severe lower gastrointestinal bleeding in Crohn’s disease . World J Gastroenterol 2021; 27(19): 2353-2365
- URL: https://www.wjgnet.com/1007-9327/full/v27/i19/2353.htm
- DOI: https://dx.doi.org/10.3748/wjg.v27.i19.2353