Retrospective Study
Copyright ©The Author(s) 2021.
World J Gastroenterol. May 14, 2021; 27(18): 2205-2218
Published online May 14, 2021. doi: 10.3748/wjg.v27.i18.2205
Table 2 Clinical and perioperative characteristics of patients with hepatocellular carcinoma in Milan criteria who underwent surgical resection and radiofrequency ablation
Before PSM
After PSM
RFA (n = 165)
Surgery (n = 429)
P value
RFA (n = 136)
Surgery (n = 136)
P value
Operative time (min) median (range)25 (5-250)205 (55-600)0.00225 (5-250)190 (55-600)0.001
Blood transfusion, n (%)13 (8)66 (15)0.0111(8)23 (17)0.04
Dindo-Clavien Classification, n (%)0.0010.002
I-II163 (99)378 (91)134 (98)121 (89)
III-IV2 (1)38 (9)2 (1)15 (11)
Postoperative complication, n (%) 0.0010.002
Yes31 (19)188 (44)28 (21)75 (55)
No134 (81)241 (56)108 (79)61 (45)
Type of complication, n (%)
Liver failure1 (1)35 (8)0.0021 (0.7)14 (10)0.001
Ascites3 (2)60 (14)0.0033 (2)17 (12)0.002
Biliary leakage0 (0)9 (2)0.0640 (0)3 (2)0.25
Hemorrhage4 (2)19 (4)0.3403 (2)11 (8)0.51
Systemic Infection4 (2)30 (7)0.034 (3)14 (10)0.03
Intra-abdominal abscess0 (0)23 (5)0.000 (0)8 (6)0.007
Wound infection2 (1)12 (3)0.372 (1)7 (5)0.17
Portal thrombosis1 (1)3 (1)1.007 1 (0.7)2 (1)1
Pulmonary7 (4)33 (8)0.156 (4)15 (11)0.07
Cardiac1 (1)18 (4)0.031 (0.7)8 (6)0.03
Renal1 (1)18 (4)0.031 (0.7)6 (4)0.12
Reoperation, n (%)0 (0)7 (2)0.190 (0)2 (1)0.5
Postoperative treatment, n (%)3 (2)19 (4)0.153 (2)10 (7)0.08
Length of hospital stay median (range)2 (1-23)6 (1-203)0.002 (1-23)7 (1-203)0.00
Mortality 90 d, n (%)3 (2)13 (3)0.0013 (2)4 (3)1

  • Citation: Conticchio M, Inchingolo R, Delvecchio A, Laera L, Ratti F, Gelli M, Anelli F, Laurent A, Vitali G, Magistri P, Assirati G, Felli E, Wakabayashi T, Pessaux P, Piardi T, di Benedetto F, de'Angelis N, Briceño J, Rampoldi A, Adam R, Cherqui D, Aldrighetti LA, Memeo R. Radiofrequency ablation vs surgical resection in elderly patients with hepatocellular carcinoma in Milan criteria. World J Gastroenterol 2021; 27(18): 2205-2218
  • URL: https://www.wjgnet.com/1007-9327/full/v27/i18/2205.htm
  • DOI: https://dx.doi.org/10.3748/wjg.v27.i18.2205