Copyright
©The Author(s) 2021.
World J Gastroenterol. May 14, 2021; 27(18): 2205-2218
Published online May 14, 2021. doi: 10.3748/wjg.v27.i18.2205
Published online May 14, 2021. doi: 10.3748/wjg.v27.i18.2205
Table 1 Preoperative and clinical characteristics of patients with hepatocellular carcinoma in Milan criteria who underwent surgical resection and radiofrequency ablation
| Before PSM | After PSM | |||||
| RFA (n = 165) | Surgery (n = 429) | P value | RFA (n = 136) | Surgery (n = 136) | P value | |
| Male, n (%) | 116 (70) | 319 (74) | 0.35 | 98 (72) | 104 (76) | 0.48 |
| Age (yr) median (range) | 75 (70-89) | 74.9 (70-90) | 0.71 | 75 (70-88) | 74.7 (70-86.1) | 0.56 |
| BMI (kg/cm²) median (range) | 26.7 (19-51) | 26.7 (19-52) | 0.37 | 26.7 (19-51) | 26 (21-41) | 0.85 |
| Co-morbidities > 2, n (%) | 107 (64) | 142 (33) | 0.001 | 83 (61) | 81 (60) | 0.90 |
| Cause of Cirrhosis n (%) | 0.002 | 0.11 | ||||
| Hepatitis C virus | 89 (54) | 217 (50) | 73 (54) | 68 (50) | ||
| Hepatitis B virus | 10 (6) | 80 (19) | 10 (7) | 22 (16) | ||
| Alcohol | 37 (22) | 60 (14) | 31(23) | 23 (17) | ||
| Others | 29 (18) | 72 (17) | 22 (16) | 23 (17) | ||
| ASA score, n (%) | 0.004 | 0.59 | ||||
| I-II | 45 (27) | 172 (40) | 41 (30) | 36 (26) | ||
| III-IV | 120 (73) | 257 (60) | 95 (70) | 100 (74) | ||
| Blood tests median (range) | ||||||
| Bilirubin (mg/dL) | 1 (0.2-2.8) | 0.9 (0.18-4.5) | 0.41 | 1 (0.2-2.8) | 0.8 (0.2-4.5) | 0.02 |
| Creatinine (mg/dL) | 0.9 (0.5-2.5) | 1 (0.2-2.5) | 0.03 | 0.9 (0.5-2.3) | 0.9 (0.4-2.5) | 0.02 |
| Platelet count × 109/L | 131 (10-856) | 178 (45-900) | 0.00 | 131.5 (10-856) | 155 (47-573) | 0.57 |
| INR | 1.1 (0.9-2.4) | 1.2 (0.6-2.5) | 0.00 | 1.1 (0.9-2.4) | 1.1 (0.8-2.5) | 0.00 |
| Child Pugh, n (%) | 0.52 | 0.87 | ||||
| A | 139 (84) | 370 (86) | 114 (84) | 116 (85) | ||
| B | 26 (16) | 59 (14) | 22 (16) | 20 (15) | ||
| MELD median (range) | 8 (6-18) | 6 (6-17) | 0.00 | 8 (6-18) | 8 (6-17) | 0.05 |
| Tumors number, n (%) | 0.07 | 0.71 | ||||
| Single nodule | 142 (86) | 392 (91) | 117 (86) | 120 (88) | ||
| Multi nodules | 23 (14) | 37 (9) | 19 (14) | 16 (12) | ||
| Tumor size (mm) n (%) | 24 (10-50) | 30 (7-50) | 0.00 | 25 (10-50) | 24.5 (7-50) | 0.9 |
| < 20 | 49 (30) | 33 (8) | 0.00 | 36 (26) | 28 (21) | 0.31 |
| 20-50 | 116 (70) | 396 (92) | 100 (74) | 108 (79) | ||
| Bilobar tumor, n (%) | 8 (5) | 8 (2) | 0.08 | 6 (4) | 2 (1) | 0.28 |
| Tumor location, n (%) | 0.28 | 0.17 | ||||
| 1 | 2 (1) | 8 (2) | 1 (0.7) | 1 (0.7) | ||
| 2 | 14 (8) | 41 (10) | 13 (9) | 14 (10) | ||
| 3 | 12 (7) | 42 (10) | 10 (7) | 20 (15) | ||
| 4 | 20 (12) | 53 (12) | 15 (11) | 13 (9) | ||
| 5 | 28 (17) | 63 (15) | 21 (15) | 27 (19) | ||
| 6 | 27 (16) | 87 (20) | 23 (17) | 29 (21) | ||
| 7 | 18 (11) | 60 (14) | 16 (12) | 11 (8) | ||
| 8 | 44 (28) | 75 (17) | 37 (27) | 21 (15) | ||
| Histologically proven, n (%) | 42 (25) | 115 (27) | 0.75 | 36 (26) | 42 (31) | 0.50 |
| Previous treatment, n (%) | 53 (32) | 53 (12) | 0.00 | 42 (31) | 21 (15) | 0.004 |
- Citation: Conticchio M, Inchingolo R, Delvecchio A, Laera L, Ratti F, Gelli M, Anelli F, Laurent A, Vitali G, Magistri P, Assirati G, Felli E, Wakabayashi T, Pessaux P, Piardi T, di Benedetto F, de'Angelis N, Briceño J, Rampoldi A, Adam R, Cherqui D, Aldrighetti LA, Memeo R. Radiofrequency ablation vs surgical resection in elderly patients with hepatocellular carcinoma in Milan criteria. World J Gastroenterol 2021; 27(18): 2205-2218
- URL: https://www.wjgnet.com/1007-9327/full/v27/i18/2205.htm
- DOI: https://dx.doi.org/10.3748/wjg.v27.i18.2205