Protective effect and mechanisms of action of Mongolian medicine Sulongga-4 on pyloric ligation-induced gastroduodenal ulcer in rats

Table 3 Top 10 Kyoto Encyclopedia of Genes and Genomes pathways enriched with differentially expressed mRNAs in duodenal tissue from rats the study groups

Treatment	KEGG pathway	P value
Shame vs PL	Complement and coagulation cascades	3.93 × 10-9
	Staphylococcus aureus infection	4.53 × 10-9
	Cytokine-cytokine receptor interaction	6.48 × 10-7
	Hematopoietic cell lineage	9.84 × 10-6
	Rheumatoid arthritis	2.78 × 10-5
	Osteoclast differentiation	4.40 × 10-5
	PI3K-Akt signalling pathway	2.13 × 10-4
	Tuberculosis	2.89 × 10-4
	ECM-receptor interaction	3.02 × 10-4
	Amoebiasis	3.37 × 10-4
PL vs SL-4	Maturity onset diabetes of the young	2.10 × 10-7
	Complement and coagulation cascades	7.39 × 10-6
	Staphylococcus aureus infection	7.99 × 10-5
	Regulation of autophagy	2.26 × 10-3
	Type II diabetes mellitus	8.47 × 10-3
	Longevity regulating pathway—multiple species	1.51 × 10-2
	Phototransduction	2.05 × 10-2
	Mucin type O-Glycan biosynthesis	2.35 × 10-2
	Porphyrin and chlorophyll metabolism	3.51 × 10-2
	Longevity regulating pathway	4.01 × 10-2

KEGG: Kyoto Encyclopedia of Genes and Genomes; Sham: PL: Pyloric ligation; Sham operation; SL-4: Sulongga-4 decoction.