Primary localized gastric amyloidosis: A scoping review of the literature from clinical presentations to prognosis

Figure 1 Pathological findings from a 70-year-old woman with localized gastric amyloidosis. The patient came to the hospital with a chief complaint of hematemesis for 2 wk. A and B: Endoscopic findings show multiple congested fragile ulcers scattered in the gastric body and fundus. A 4.0 cm × 4.0 cm area of the mucosa with edema, ulcers, and poorly delineated boundaries was observed in the anterior wall of the gastric body and fundus. The lesion appeared as a rough, congested area with edema, localized superficial fragile ulcers and active bleeding. Spot-like congested erosions exhibited a scattered distribution in the mucus of the sinus; C: CT reflected diffusely thickened gastric walls and shallow folds of the mucosa, while no abnormalities were observed in the enhanced images; D: H&E staining revealed massive amyloid fibrous connective tissues deposited in the interstitium with inflammatory cell infiltration; E and F: Congo red staining confirmed the existence of the amyloid protein (E: Congo red, × 200 magnification; F: Congo red, × 400 magnification).