Basic Study
Copyright ©The Author(s) 2020.
World J Gastroenterol. Mar 7, 2020; 26(9): 918-932
Published online Mar 7, 2020. doi: 10.3748/wjg.v26.i9.918
Figure 3
Figure 3 Regulation of KMO is involved in induction of Foxp3+ Treg cells. A: Serial sections of the colons of the indicated mice were stained for Foxp3 and counterstained with hematoxylin. B–E: CD4+Foxp3+ cells and CD11c+CD103+ cells were analyzed using flow cytometry on colonic LP cells and MLN cells, respectively, from indicated mice, gated on 7-AAD-CD45.2+ cells. Representative flow cytometry plots and cumulative datagraphical summary are depicted. Data are representative of at least five independent experiments with similar results: aP < 0.05 vs TNBS-treated KMO+/+ mice group; cP < 0.05 vs KMO−/− Vehicle group. KMO: Kynurenine 3-monooxygenase; TNBS: Trinitrobenzene sulfonic acid.