lncRNACNN3-206 activates intestinal epithelial cell apoptosis and invasion by sponging miR-212, an implication for Crohn's disease

Figure 8 Changes in the percentage of CD4+ lymphocytes in the spleen of the mouse Crohn’s Disease model after manipulation of lncRNACNN3-206 expression levels. A: The Th1, Th2, Th17, and Treg cells were sorted and counted by flow cytometry analysis; B: Calculation of the ratios of Th1/Th2 and Th17/Treg ratios. The Th1/Th2 ratio in the TNBS group was > 1, while the Th1/Th2 ratio was < 1 after knockdown of si-lncRNACNN3-206 (TNBS + si-lncRNACNN3-206). The Th17/Treg ratio in the TNBS group was > 1, but the Th17/Treg ratio was < 1, after knockdown of si-lncRNACNN3-206 (TNBS + si-lncRNACNN3-206).