Nomograms predicting long-term survival in patients with invasive intraductal papillary mucinous neoplasms of the pancreas: A population-based study

Table 1 Patient demographics and clinical characteristics (n = 1219)

Characteristics	Training cohort (n = 853)		Validation cohort (n = 366)
	Number of patients	Percent (%)	Number of patients	Percent (%)
Age (yr)
≤ 60	218	25.6	70	19.1
60-69	276	32.4	127	34.7
70-79	281	32.8	131	35.8
≥ 80	78	9.2	38	10.4
Sex
Male	470	55.1	201	54.9
Female	383	44.9	165	45.1
Race
White	694	81.4	316	86.3
Others1	159	18.6	50	13.7
Marital status
Married	558	65.4	233	63.7
Unmarried2	295	34.6	133	36.3
Grade
Well differentiated	187	21.9	66	18.0
Moderately differentiated	320	37.5	157	42.9
Poorly differentiated/Undifferentiated	162	19.0	73	19.9
Unknown	184	21.6	70	19.1
Tumor location
Head	181	21.2	232	63.4
Body/tail	553	64.8	75	20.5
Other3	119	14.0	59	16.1
T stage
T1	124	14.5	57	15.6
T2	206	24.2	71	19.4
T3	468	54.9	207	56.5
T4	55	6.4	31	8.5
N stage
N0	497	58.3	209	57.1
N1	356	41.7	157	42.9
M stage
M0	800	93.8	346	94.5
M1	53	6.2	20	5.5
Clinical stage
I	267	31.3	95	26.0
II	500	58.6	231	63.0
III	33	3.9	20	5.5
IV	53	6.2	20	5.5
Tumor size
< 3 cm	302	35.4	146	39.9
3-6 cm	417	48.9	168	45.9
> 6 cm	134	15.7	52	14.2
Surgical type
Partial/localized pancreatectomy	152	17.8	65	17.8
Total pancreatectomy	122	14.3	45	12.3
Extensive pancreatoduodenectomy	579	67.9	256	69.9
Radiation
None	609	71.4	248	67.8
Adjuvant radiotherapy solely	222	26.0	107	29.2
Others4	22	2.6	11	3.0
Chemotherapy
No/unknown	435	51.0	180	49.2
Yes	418	49.0	186	50.8

¹Including Black, Asian, Pacific Islander, American Indian, and Alaska Native;

²Including single (never married), widowed, and divorced;

³Including pancreatic duct, overlapping lesion of the pancreas, and other specified parts of the pancreas;

⁴Including neoadjuvant radiotherapy, and radiotherapy before and after surgery.