Development of a prognostic model for one-year surgery risk in Crohn’s disease patients: A retrospective study

Table 2 Factors associated with possibility of one-year surgery in patients with Crohn’s disease

Factor	Univariate analysis			Multivariable logistic regression
	OR	95%CI	P	OR	95%CI	P
Gender (male vs female)	0.793	0.565-1.113	0.180
Age (yr)	1.012	0.999-1.025	0.070
Location (L1 vs L2/L3/L4)
L2	0.729	0.401-1.324	0.300
L3	0.853	0.568-1.282	0.445
L4	0.988	0.526-1.855	0.971
Behavior (B1 vs B2/B3)
B2	5.771	3.837-8.680	< 0.001	6.693	3.437-13.032	< 0.001
B3	14.998	10.113-22.242	< 0.001	14.405	7.208-28.790	< 0.001
Maximum BWT	1.391	1.278-1.514	< 0.001	1.965	1.660-2.327	< 0.001
Drinking	1.702	0.970-2.985	0.064
Smoking	4.359	3.034-6.262	< 0.001	4.135	2.149-7.953	< 0.001
BMI	0.901	0.854-0.950	< 0.001	0.873	0.786-0.968	0.01
Previous perianal surgery	6.776	4.943-9.288	< 0.001	9.483	5.317-16.912	< 0.001
Previous intestinal surgery	5.199	3.794-7.125	< 0.001	8.887	5.045-15.656	< 0.001
5-aminosalicylic acid use	0.709	0.485-1.038	0.077
Immunosuppressants use	0.974	0.700-1.355	0.877
Corticosteroid use	0.931	0.697-1.243	0.627
Biologics use	0.283	0.204-0.392	< 0.001	0.264	0.146-0.476	< 0.001
Exclusive enteral nutrition use	0.359	0.235-0.550	< 0.001	0.089	0.038-0.205	< 0.001
CRP at diagnosis (pathological vs normal)	1.020	1.014-1.026	< 0.001	1.022	1.009-1.036	0.001
ESR at diagnosis (pathological vs normal)	1.005	1.000-1.010	0.058
Alb at diagnosis (pathological vs normal)	0.981	0.962-1.001	0.058

CI: Confidence interval; BWT: Bowel wall thickness; BMI: Body mass index; CRP: C-reactive protein; ESR: Erythrocyte sedimentation rate; Alb: Albumin.