Colonic vitamin D receptor expression is inversely associated with disease activity and jumonji domain-containing 3 in active ulcerative colitis

Table 1 Demographic characteristics of ulcerative colitis patients and controls

Variable	UC patients, n = 100	HC, n = 56	P value
Age [mean (SD), yr]	45.5 (14.2)	45.8 (10.0)	0.8731
Sex (female: male)	57:43	32:24	0.9862
Smoker, n (%)	45 (45.0)	21 (37.5)	0.3632
BMI [mean (SD), kg/m2]	21.2 (3.4)	20.4 (2.1)	0.1011
25 (OH) D [mean (SD), nmol/L]	13.7 (2.8)	16.2 (2.5)	< 0.0011
Disease Location, n (%)
Ulcerative proctitis (E1)	8 (8.0)	-	-
Left-sided colitis (E2)	54 (54.0)	-	-
Extensive colitis (E3)	38 (38.0)	-	-
Severity of UC, n (%)
Mild	29 (29.0)	-	-
Moderate	32 (32.0)	-	-
Severe	39 (39.0)	-	-
Current medications, n (%)
SASP/5-ASA	80 (80.0)	-	-
Immunosuppressants	2 (2.0)	-	-
Steroids	31 (31.0)	-	-
Biologics	4 (4.0)	-	-
Others	22 (22.0)	-	-
Duration of disease mean (SD), yr	5.4 (6.0)	-	-

¹Independent sample t tests.

²χ² test. 5-ASA: 5-Aminosalicylic acid; SASP: Sulfasalazine; SD: Standard deviation; UC: Ulcerative colitis.