Nimbolide inhibits tumor growth by restoring hepatic tight junction protein expression and reduced inflammation in an experimental hepatocarcinogenesis

doi:10.3748/wjg.v26.i45.7131

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Dec 7, 2020 (publication date) through Apr 26, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Dec 7, 2020; 26(45): 7131-7152
Published online Dec 7, 2020. doi: 10.3748/wjg.v26.i45.7131

Table 1 Mean tumor volume and tumor growth inhibition (%) in the experimental mice

Experimental groups	Mean tumor volume (mm³)	Tumor growth inhibition (%)
HCC	78.45 ± 11.87	-
HCC + nimbolide	37.60 ± 5.26^e	52.08
HCC + doxorubicin	35.73 ± 8.09^e	54.45

^eP < 0.01. HCC: Hepatocellular carcinoma.

Citation: Ram AK, Vairappan B, Srinivas BH. Nimbolide inhibits tumor growth by restoring hepatic tight junction protein expression and reduced inflammation in an experimental hepatocarcinogenesis. World J Gastroenterol 2020; 26(45): 7131-7152
URL: https://www.wjgnet.com/1007-9327/full/v26/i45/7131.htm
DOI: https://dx.doi.org/10.3748/wjg.v26.i45.7131