Dihydromyricetin ameliorates chronic liver injury by reducing pyroptosis

Figure 4 Changes in the expression of caspase-1, the core protein of pyroptosis, were observed by immunohistochemistry. A-D: The immunohistochemical results of caspase-1 in the control, CCl₄, vehicle and dihydromyricetin groups, respectively; E: Statistical graph of the immunohistochemical results of caspase-1 in the above four groups. There was very little caspase-1 in the control group; while in the CCl₄ and vehicle groups, a large amount of caspase-1 was observed; but caspase-1 was significantly decreased in the dihydromyricetin group. The scale bar refers to 100 μm. ^aP < 0.01 vs control group; ^bP < 0.05 vs vehicle group; n = 3. DHM: Dihydromyricetin.