Associations of content and gene polymorphism of macrophage inhibitory factor-1 and chronic hepatitis C virus infection

Table 4 Correlation between rs1059519 gene polymorphism and other parameters in chronic hepatitis C patients

Group	n	Genotype			χ2	P value	Allele		χ2	P value	OR value (95%CI)
		CC	CG	GG			C	G
Sex
M	99	10 (0.101)	40 (0.404)	49 (0.495)	2.906	0.233	60 (0.303)	138 (0.697)	2.102	0.147	0.703 (0.437-1.133)
F	79	7 (0.089)	23 (0.291)	49 (0.620)			37 (0.234)	121 (0.766)
Age in yr
≤ 40	84	8 (0.095)	31 (0.369)	45 (0.536)	0.166	0.920	47 (0.280)	121 (0.720)	0.085	0.770	0.933 (0.585-1.488)
> 40	94	9 (0.096)	32 (0.340)	53 (0.564)			50 (0.266)	138 (0.734)
ALT in U/L
≤ 50	82	9 (0.094)	33 (0.344)	54 (0.562)	0.122	0.941	51 (0.266)	141 (0.734)	0.099	0.753	1.07 (0.6759-1.720)
> 50	96	8 (0.098)	30 (0.366)	44 (0.537)			46 (0.280)	118 (0.720)
TBIL in mol/L
≤ 34.2	144	12 (0.083)	49 (0.340)	83 (0.576)	2.480	0.289	73 (0.253)	215 (0.747)	2.746	0.097	1.606 (0.914-2.823)
> 34.2	34	5 (0.147)	14 (0.412)	15 (0.441)			24 (0.353)	44 (0.647)
ALB in g/L
≤ 40	82	9 (0.110)	25 (0.305)	48 (0.585)	1.692	0.429	43 (0.262)	121 (0.738)	0.162	0.687	1.101 (0.689-1.760)
> 40	96	8 (0.083)	38 (0.396)	50 (0.521)			54 (0.281)	138 (0.719)
CIV in ng/mL
≤ 30	120	14 (0.117)	44 (0.367)	62 (0.517)	2.664	0.264	42 (0.300)	168 (0.700)	2.816	0.093	0.641 (0.380-1.080)
> 30	58	3 (0.052)	19 (0.328)	36 (0.621)			25 (0.216)	91 (0.784)
PLT as 109/L
≤ 100	43	5 (0.116)	16 (0.372)	22 (0.512)	0.465	0.793	26 (0.302)	60 (0.698)	0.510	0.475	0.823 (0.483-1.404)
> 100	135	12 (0.089)	47 (0.348)	76 (0.563)			71 (0.263)	199 (0.737)
HCV RNA as copies/mL
≤ 2 × 106	69	9 (0.130)	21 (0.304)	39 (0.565)	2.266	0.322	39 (0.283)	99 (0.717)	0.117	0.733	0.920 (0.571-1.483)
> 2 × 106	109	8 (0.073)	42 (0.385)	59 (0.541)			58 (0.266)	160 (0.734)

ALB: Albumin; ALT: Alanine aminotransferase; CIV: Type IV collagen; HCV: Hepatitis C virus; OR: Odds ratio; PLT: Platelet; TBIL: Total bilirubin.