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Copyright ©The Author(s) 2020.
World J Gastroenterol. Nov 7, 2020; 26(41): 6322-6334
Published online Nov 7, 2020. doi: 10.3748/wjg.v26.i41.6322
Table 2 Diagnostic and therapeutic management of gastroesophageal reflux disease in adult patients with cystic fibrosis
Adult patients
Typical symptomsHeartburn, regurgitation
Diagnostic tests indications
PPIs TrialClassical symptoms
Barium SwallowNot for GERD diagnosis
EndoscopyIn presence of alarm symptoms
Esophageal biopsyExclude non-GERD diagnosis
Esophageal manometry
TherapyPPI for eight weeks
Additional optionsLifestyle modifications
Alginate or antiacide for symptoms relief
Complications associated to therapyClostridium difficile infection
Risk of community-acquired pneumonia
with a short-term PPI