Dynamic contrast-enhanced magnetic resonance imaging and diffusion-weighted imaging in the activity staging of terminal ileum Crohn's disease

Figure 5 Receiver operating characteristic curve analysis. Receiver operating characteristic curve analysis shows high accuracy of K^trans (areas under the curve [AUC] = 0.76), V_e (AUC = 0.78), K_ep (AUC = 0.68), apparent diffusion coefficient (AUC = 0.89) and Magnetic Resonance Index of Activity (AUC = 0.91) for differentiating inactive from active Crohn’s disease. Accuracy of combining the K^trans, K_ep and V_e (AUC = 0.80) is higher than the individual dynamic contrast-enhanced magnetic resonance imaging parameters. The highest AUC is observed when combining dynamic contrast-enhanced magnetic resonance imaging and diffusion-weighted imaging parameters (AUC = 0.95). ROC: Receiver operating characteristic; ADC: Apparent diffusion coefficient; DCE-MRI: Dynamic contrast-enhanced magnetic resonance imaging; MaRIA: Magnetic Resonance Index of Activity.