Histopathological validation of magnifying endoscopy for diagnosis of mixed-histological-type early gastric cancer

Table 2 Clinicopathological characteristics and treatment outcome of the 49 mixed histological-type early gastric cancers investigated in this study (n = 49), n (%)

Patient characteristics
Age (yr), mean ± SD	71.7 ± 9.5
Male	34 (69.4)
Endoscopic examination
Location
Upper third	4 (8.2)
Middle third	12 (24.5)
Lower third	33 (67.3)
Macroscopic types
Elevated	5 (10.2)
Flat	0
Depressed	44 (89.8)
Preoperative biopsy results
Only DT component (tub1, tub2 or pap)	36 (73.5)
UDT component (por1, por2, sig or muc) with or without DT component	13 (26.5)
ME-NBI findings of UDT gastric cancer	12 (24.5)
Histopathological examination
Tumor diameter (mm), mean ± SD	23.3 ± 14.4
Depth
Mucosal	34 (69.4)
Submucosal, < 500 um	7 (14.3)
Submucosal, ≥ 500 um	8 (16.3)
Lymphovascular invasion
Lymphoid invasion	10 (20.4)
Vascular invasion	2 (4.1)
Vertical margin positive	2 (4.1)
Horizontal margin positive	1 (2.0)
Ulcerative finding	10 (20.4)
Predominant histological type
Differentiated	36 (73.5)
Undifferentiated	13 (26.5)
The whole mucosal layer extension of UDT component	33 (67.3)
Exposure of UDT cancer to the surface of the mucosa	39 (79.6)
Clear border between DT and UDT components	17 (34.7)
Treatment outcome
Curative resection	24 (49.0)
Additional surgery	19 (38.8)
Lymph node metastasis	1 (2.0)
Recurrence	0

ME-NBI: Magnifying endoscopy with narrow-band imaging; DT: Differentiated-type; UDT: Undifferentiated-type.